Applied Neurobiological Imaging, Dr. Katherine L. Narr

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Identifying the cingulate gyrus component of the cingulum in DTIStudio using a multiple ROI approach

Written 7/25/08 by Aimee Zisner. Updated 02/17/2009 by Owen Phillips. Email email ophillip at loni dot ucla dot edu if you have any questions. This protocol explains how to identify the cingulate gyrus component of the cingulum in DTIStudio. For more information on identifying white matter tracts using DTIStudio, see http://www.loni.ucla.edu/~narr/protocols.php or the related protocols below.

Note: Tractography shown in this protocol was performed in DTIStudio using 30 direction diffusion data.

To identify the cingulate gyrus component of the cingulum (CGC):

First ROI First ROI: Identify the coronal slice intersecting the middle of the splenium of the corpus callosum using the mid-sagittal slice. Select all fibers superior to the corpus callosum on the side of the hemisphere of interest.
Second ROI: Identify the most central coronal slice of the corpus callosum using the mid-sagittal slice. Select all remaining fibers superior to the corpus callosum.

* Be sure to remove all fibers that are clearly not a part of the tract.
Second ROI
Sagittal view of the cingulate gyrus Sagittal view of the cingulate gyrus component of the cingulum

References

  1. Wakana S, Caprihan A, Panzenboeck MM, Fallon JH, Perry M, Gollub RL, Hua K, Zhang J, Jiang H, Dubey P, Blitz A, van Zijl P, Mori S (2007). Reproducibility of quantitative tractography methods applied to cerebral white matter. Neuroimage. 2007 Jul 1;36(3):630-44. Epub 2007 Mar 20. Click here to view.

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